INS and systemic sclerosis: In univariate analysis, ISI was significantly correlated with BMI (rho = -0.468, p = 0.002), fasting insulin (rho = -0.715, p <0.001), and mRSS (rho = 0.422, p = 0.006), while no association emerged with age (rho = -0.213, p = 0.181), FPG (rho = -0.248, p = 0.118), disease duration (rho = -0.208, p = 0.191), and UCLA-GIT score (rho = -0.101, p = 0.529) in SSc patients.