A case-control study of fibrosis (ie, not including steatosis alone) in adults aged 30–70 years (n=213 with fibrosis) by Taharboucht et al32 also reported greater cIMT and greater carotid-femoral PWV in the presence of fibrosis, even after the adjustment for age, sex, smoking, abdominal obesity, overall obesity, hypertension, dyslipidemia, GGT, ALT, insulin resistance, and CRP. The gene discussed is CRP; the disease is obesity due to melanocortin 4 receptor deficiency.