In order to further explore the mechanism by which B3GNT3 regulates the downstream target genes of mRNAs to inhibit the growth of ESCC, the KEGG pathway mainly involved in the candidate target genes was divided into five branches: cell process, Environmental Information Processing, Human Disease, Metabolism, Organismal Systems (Fig. 7a). Here, B3GNT3 is linked to esophageal squamous cell carcinoma.