Previous studies have shown that B3GNT3 levels are positively correlated with lymph node metastasis in non-small cell lung cancer and cervical cancer, suggesting that B3GNT3 may play a role in the progression of these two tumors14,15 In addition, Ho et al. showed that overexpression of B3GNT3 could inhibit the invasion and migration of neuroblastoma cells24. Here, B3GNT3 is linked to non-small cell lung carcinoma.