Recently, many studies have reported that a group of patients with grade I meningiomas have significantly worse outcomes than others.[27] Considering the association between the SULT1E1+ subpopulation and tumor recurrence, it will be important to determine the difference in prognosis between grade I meningiomas with and without the SULT1E1+ subpopulation in future research. The gene discussed is SULT1E1; the disease is neoplasm.