INS and diabetes mellitus: Using a model developed by the World Health Organization (13), the most relevant factors can be categorized as person-related (e.g. younger age, low health literacy, being male, having depression), socio-economic (e.g. affordability of medication, less social support), diabetes-related (e.g. shorter diabetes duration), treatment-related (e.g. more complicated medication regimen, more side-effects, insulin use) and healthcare-related (e.g. patient-clinician communication, lack of time for adequate care, lack of integrated care) (14–16).