CPT1A and colonic neoplasm: For instance, the uptake, utilization and enhanced intracellular trafficking of adipocyte-derived FA has been shown to promote breast cancer progression (Yang et al., 2018), as well as to be critical in colon cancer, whereby CPT1A-dependent FAO upregulates Wnt/β-catenin signaling by regulating β-catenin acetylation (Xiong et al., 2020).