,48 Even though circulating glucose levels in 14-h fasting mice undergoing CKD-dependent sarcopenia or sham operation did not differ (116.2 ± 14.7 mg/dL in mice with sarcopenia versus 107.7 ± 18.7 mg/dL in sham), insulin levels following an oral glucose exposure were significantly higher in wild type mice with sarcopenia (Figures 2A and 2B, black symbols). The gene discussed is INS; the disease is chronic kidney disease.