AMPD1 and chronic kidney disease: Importantly, the beneficial effects observed in AMPD1 KO mice undergoing CKD were not a consequence of lower intake of the high protein diet as no significant differences were observed in daily (2.62 ± 0.22 g/day versus 2.34 ± 0.16 in wild type mice with CKD) and 4-week cumulative food consumption between strains.