Evaluation of CAM tumors developing from grafted RB cells (Figure 6(a)) as well as quantification of tumor weight (Figure 6(b)) and size (Figure 6(c)) showed that etoposide-resistant, INPP4B overexpressing RB355 cells developed significantly smaller tumors (Figures 6(a) and 6(b)) than control cells and likewise exhibited weight (Figure 6(b)). The gene discussed is INPP4B; the disease is neoplasm.