INPP4B and malignant colon neoplasm: By contrast, INPP4B overexpression in acute myeloid leukemia cells increased their colony formation potential [32], and INPP4B overexpression likewise led to enhanced anchorage-independent growth in cancer entities, in which INPP4B was identified as an oncogene, e.g., gallbladder cancer, colon cancer, and acute myeloid leukemia cell lines [29, 34, 51].