CD4 and infection: Some studies have also suggested a relation between infection in these patients and other biomarkers such as IL-6 and nutritional status (6), serum levels of IgA antibodies against NDO-HSA (7), CCL2 chemokine associated with IFN-γ (8), and IgM profile against NDO-HSA, LID-1, and NDOLID antigens, and monocytes and CD4+ lymphocyte frequency (9), beyond arginase activity (10) as a protective marker against this infection.