Loss of GABRQ*-containing neurons is an indicator of early social-emotional cognitive decline in frontotemporal dementia (81), IL6R* has been associated with memory domain scores, and Alzheimer’s disease pathology (cerebrospinal fluid pTau and Aβ42/40 ratio) (82), RAB27B regulates α-Synuclein, which is a primary indicator of Parkinson’s disease and dementia with Lewy bodies (83), and DTNB is an indicator of extent of neuronal injury and inflammation in Alzheimer’s disease (84). The gene discussed is IL6R; the disease is Alzheimer disease.