RAB27B and early-onset autosomal dominant Alzheimer disease: Loss of GABRQ*-containing neurons is an indicator of early social-emotional cognitive decline in frontotemporal dementia (81), IL6R* has been associated with memory domain scores, and Alzheimer’s disease pathology (cerebrospinal fluid pTau and Aβ42/40 ratio) (82), RAB27B regulates α-Synuclein, which is a primary indicator of Parkinson’s disease and dementia with Lewy bodies (83), and DTNB is an indicator of extent of neuronal injury and inflammation in Alzheimer’s disease (84).