NLRP3 and familial cold autoinflammatory syndrome: For example, the autoinflammatory diseases tumor necrosis factor receptor-associated periodic syndrome (TRAPS), familial cold autoinflammatory syndrome (FCAS; NLRP3-associated autoinflammatory disease-mild) and familial Mediterranean fever (FMF) as a group differed from the healthy subjects and other diseases by similar signatures, including lymphocyte and B-cell counts that trended higher than other diseases, which to the best of our knowledge has not been described for this group of diseases.