Gamete‐level immunogenetic incompatibility have also been found on risk of infertility in humans (Jokiniemi, Kuusipalo, et al., 2020; Jokiniemi, Magris, et al., 2020), and cryptic haplo‐specific gamete selection have been described resulting in offspring with optimal MHC immune genes (Lenz et al., 2018). Here, HLA-C is linked to Infertility.