Aeberli et al. found in Swedish children that dietary intake of antioxidant vitamins (vitamin E and vitamin C and β-carotene) was significantly associated with leptin levels (p < 0.05), suggesting that low concentrations of antioxidant vitamins may alter the genetic expression of leptin, leading to the development of leptin resistance and increasing the risk of obesity (21, 22). Here, LEP is linked to obesity disorder.