They purchased more of the following preparations: insulin (2.46% vs. 0.95%, p = 0.017), calcium channel blocker felodipine (8.42% vs. 5.62%, p = 0.036), angiotensin-converting enzyme (ACE) inhibitor ramipril (4.91% vs. 2.99%, p = 0,05), HMG CoA reductase inhibitor simvastatin (29.4% vs. 22.6%, p = 0.007), opioid analgesics ketobemidone (3.16% vs. 1.09%, p = 0.004) and fentanyl (1.75% vs. 0.58%, p = 0.021), nicotine dependence drug varenicline (5.26%–2.04%, p = 0.001), and the nitroimidazole antibiotic metronidazole (17.5% vs. 12.4%, p = 0.01). This evidence concerns the gene ACE and nicotine dependence.