INS and type 2 diabetes mellitus: Twenty-two patients, with T2D were administered premixed insulin for the first 2 months, followed by IDegAsp for 2 months (18); mean blood glucose levels (175.5 vs. 163.0 mg/dL; p = 0.004) were significantly lower in the IDegAsp phase when compared to the premixed phase measured before and after breakfast as well as before and after the evening meal (18).