INS and type 2 diabetes mellitus: Despite using varied parameters to define insulin deficiency (fasting and stimulated C-peptide, HOMA2-B%, and insulin sensitivity or HOMA2-S) and fasting C-peptide thresholds, a lower prevalence of insulin deficiency was reported in an adult South Korean (4.4%) (12) and Danish population (9.6%) (13) with new-onset presumed type 2 diabetes.