Our findings are also consistent with those from the data source publications: Kazer et al. found a core module of interferon-associated genes in HIV-1+ individuals that were highly expressed in multiple cell types; Wang et al. found a subset of CD8+ T cells expressing high levels of IFN-I associated-genes to be enriched in HIV-1+ individuals; Wilk et al. found a wide range of IFN-I-associated genes that were highly expressed by COVID-19 patients across nearly all cell types. The gene discussed is CD8A; the disease is COVID-19.