In a COVID-19 hypercytokinemia-based study, patients were observed to have upregulation of IL-1, IL-2, IL-4, IL-7, IL-10, IL-12, IL-13, IL-17, GCSF, macrophage colony-stimulating factor (MCSF), IP-10, MCP-1, MIP-1α, hepatocyte growth factor (HGF), etc. [36]. This evidence concerns the gene CSF3 and COVID-19.