KRT88P and infection: A number of HBc mutations scattered throughout the NTD (at S44, S49, R82, N92, and R98) and the linker region (at S141, L143, E145, T146, and T147) were recently found to allow, or even enhance, cccDNA formation via intracellular amplification but to impair cccDNA formation during infection (Figure 2) [9,18,59,60].