RHOT1 and breast cancer: MIENTURNET miRTarbase analysis identified ZHX2, ZBTB26, TCF12, SMARCA4, RHOT1, NRFA2, NANOGNB, MMP11, FNBP4, and DERL1 as the top 10 most significant target genes of miR-139-5p (Figure 3J) with predicted gene networks shown in Figure 3K. KEGG pathway analysis suggested that the target genes of miR-139-5p are associated with endocrine resistance, focal adhesion, lipid and atherosclerosis, apoptosis, and breast cancer (Figure 3L).