PTH and nicotine dependence: KEGG pathway analysis suggested that the target genes of the miRNAs longitudinally downmodulated by THC in cART-treated RMs were associated with: transcriptional misregulation in cancer, prostate cancer, parathyroid hormone synthesis, secretion and action, HIF-1 signaling pathway, selenocompound metabolism, Huntington disease, RNA polymerase, nicotine addiction, ferroptosis, and cholesterol metabolism (Figure 7L).