In ECs, the Reactome analysis suggests that the target genes of multiple miRNAs are associated with transcriptional regulation by RUNX1, regulation of RUNX1 expression and activity, mitotic G1-G1/S phase, cyclin D-associated events in G1, G1 phase, interleukin-4 and 13 signaling, transcriptional regulation by RUNX3, cellular senescence, disease of signal transduction, constitutive signaling by AKT1 E17k in cancer, as well as interleukin-7 signaling. The gene discussed is AKT1; the disease is cancer.