KEGG pathway analysis showed target genes of miR-206, miR-99a-5p, and miR-128-3p were associated with signaling pathways regulating: pancreatic cancer, colorectal cancer, Th17 cell differentiation, cell cycle, apelin signaling pathway, pathways regulating pluripotency of stem cells, longevity regulating pathway—multiple species, glioma, EGFR tyrosine kinase inhibitor resistance, longevity regulating pathway, prostate cancer, AGE-RAGE signaling pathway in diabetic complications, Chagas disease (Figure 5I). Here, APLN is linked to Chagas disease.