Furthermore, WikiPathways analysis suggests that the target genes of multiple miRNAs are associated with non-small-cell lung cancer, DNA damage response, hepatitis C, and hepatocellular carcinoma, as well as extracellular vesicles in the crosstalk of cardiac cells, focal adhesions, VEGFA-VEGFR2 signaling pathway, TLR4 signaling/ tolerance, and heart development. Here, TLR4 is linked to hepatocellular carcinoma.