NPSR1-AS1 and Erythema: Furthermore, the AAA1+ rate was not linked to either local (pain, swelling or erythema at the injection site) or systemic adverse events (headache, arthralgia, myalgia, chills, fatigue or lymphadenopathy) reported both after the first and second vaccine doses, because their frequencies in subjects with and without AAA1 positivity were not different (Figure 2).