GSK3B and colon adenocarcinoma: As shown by Pandurangan et al. 2013 Luteolin was identified to cause the inducement of growth arrest via inhibition of Wnt/β-catenin/glycogen synthase kinase-3 beta (GSK-3β) signaling pathway and caused promotion of apoptosis in a Caspase-3 mediated manner in HCT-15 colon adenocarcinoma cell line [45].