Serum tumor indicators on pathological types, staging, monitoring, and prognostication of lung cancer [6] with serum squamous cell carcinoma antigen (SCC) [7], carcinoembryonic antigen (CEA) [8], and neuron-specific enolase (NSE) [9] are regarded to be successful strategies for lung cancer detection; nevertheless, these are laborious techniques [10]. This evidence concerns the gene SERPINB3 and lung cancer.