To further confirm that FBXW7 and MAP4 have prognostic impacts on survival, we included clinicopathological parameters (sex, age, tumor differentiation, lymph node metastasis) and the expression of FBXW7 and MAP4 to perform univariate and multivariate Cox proportional hazards regression analyses. Here, MAP4 is linked to metastatic malignant neoplasm in the lymph nodes.