Both genes were mentioned in association with a variety of outcome events ranging from vascular to cardiac disease [11, 12, 22, 27, 30, 38, 44, 45, 54, 60–62, 65, 72, 92, 93] with PTPRN2 being a predisposing factor for cardiac disease [12, 27, 30, 38, 44, 45, 54, 61, 72, 92, 93]. The gene discussed is PTPRN2; the disease is heart disorder.