Our data showed the percentages of CD45 + PD-1 + lymphocytes, CD3 + PD-1 + T cells, and CD3 + CD4 + PD-1 + T cells were increased in the secondary peritoneal neoplasms group, compared with primary group, while Tim-3 had no statistical differences. This evidence concerns the gene HAVCR2 and peritoneal neoplasm.