ANXA5 and melanoma: The percentage of cells with nuclear fragmentation in 7,8-DHF-treated cells vs. non-treated cells is shown in Fig. 2B. Additionally, the apoptotic effect of 7,8-DHF on SK-MEL-2 and G-361 melanoma cells was evaluated after 24 h using the Annexin-V/7-ADD assay (Fig. 2C).