GSK3B and major depressive disorder: We collected plasma from the healthy subjects and patients diagnosed with BD and MDD to measure the levels of the phosphorylated (p-GSK3β) and non-phosphorylated GSK3β at ser 9 (inhibitory site), as well as phosphorylated (at ser 505) and non-phosphorylated Ca2+-dependent phospholipase A2 (p-cPLA2 and cPLA2 respectively), AA and PGE2.