EGF, NGF and KLK 1 are also the differentiation maker for GCT, whereas p130Cas deficiency did not alter the expression levels of keratin 19 (K19) which is a marker for excretory ducts, and keratin 18 (K18) which expresses in both acinar and duct cells (Fig. 5A). The gene discussed is KRT18; the disease is granular cell tumor.