However, during the EMT process, the interaction between them is weakened; β-catenin dissociates from the calmodulin complex and is translocated to the nucleus, where it plays a regulatory role, such as increasing the expression levels of Snail and ZEB1 in HCC cells, which results in weakened cell adhesion and increased motility [30]. This evidence concerns the gene SNAI1 and hepatocellular carcinoma.