BMP1 and non-small cell lung carcinoma: This pattern is exaggerated when examining long and short isoforms in late-stage NSCLC subjects, where we observe a trend of increasing upregulation of segment 1 peptides (short BMP1 isoform) and a trend of decreasing upregulation of segment 2 peptides (long BMP1 isoform) between healthy subjects, Stage 1 and 2 NSCLC subjects, and Stage 3 and 4 NSCLC subjects (S4 Fig).