Many conditions, including neoplastic, inflammatory, and metabolic diseases are associated with high production of SAA in cats [9] but amyloidosis has been only sporadically reported in not predisposed breeds [10–13]; recently, the differences in SAA genetic sequences proved to not contribute to the pathogenesis of feline AA-amyloidosis both in Japanese domestic cats [14] and in Abyssinian breed [15]. This evidence concerns the gene SAA1 and AA amyloidosis.