This also provides novel insights on p53-mediated cell fate decisions [84], and could be particularly useful to eliminate cells that underwent SIPS, in which p53 is normally a driver [73], but it also could be a useful approach in cancer cells with mutated p53 induced to senescence after exposure to chemo or radiotherapy, which are believed to contribute to tumour relapse [11]. The gene discussed is TP53; the disease is neoplasm.