Research has indicated that pro‐inflammatory factors such as interleukin (IL)‐1β, IL‐17, and IL‐8, NOD‐like receptor protein 3 (NLRP3) inflammasome, tumor necrosis factor‐alpha (TNF‐α), and anti‐inflammatory factors such as IL‐10, IL‐37 have all been implicated monosodium urate (MSU)‐induced gout inflammatory process.7 The gene discussed is IL1B; the disease is gout.