The DEG analysis showed that the expression of Th and memory T cell differentiation transcription factor (TF) genes TCF7 [42], LEF1 [43], STAT1 [44], STAT5B [45] and IKZF1 [46] was upregulated in the 2V7 and 2V14 groups compared with BV group (Figure 5C and S5C). The gene discussed is IKZF1; the disease is bacterial vaginosis.