In particular, NF‐κB activation leads to the transcription and functionalization of the NLRP3 inflammasome, which participates in NLRP3/caspase‐1 signaling in the pathological process of neurodegenerative diseases (Elali & Rivest, 2016; Hanslik & Ulland, 2020). This evidence concerns the gene NLRP3 and neurodegenerative disease.