Typical inflammatory pathways, such as the c‐Jun N‐terminal kinase (JNK)/nuclear factor (NF)‐κB (Bo et al., 2021; Xu et al., 2021; Yamamoto et al., 2021) and PI3K/Akt (Mizuta et al., 2020; Xue et al., 2021) pathways, are involved in the pathological processes of ARDS and nerve diseases. The gene discussed is MAPK8; the disease is acute respiratory distress syndrome.