HSCT is curative in SCID, CGD, DOCK8 deficiency, IPEX syndrome, Wiskott-Aldrich syndrome, LRBA deficiency, and LAD1, and it improves intestinal disease in STAT-1 and STAT-3 GOF syndromes, IL-10 deficiency, and IL-10R deficiency [3,41]. Here, DOCK8 is linked to hyperinsulinemic hypoglycemia, familial, 4.