Note that the expression of TIM3 and CD47 markers on NCH644 tumor cells also increased after culturing with dendrimers (see Figure 5 and Supplementary Materials): NCH644 cells responded to the use of AE2G3 by increased TIM3 expression (p = 0.03), NCH644 cells responded predominantly to AE2G3 addition, as in the case of PD-L1. This evidence concerns the gene CD47 and neoplasm.