ESR1 and neoplasm: As shown in Table 1, high expression was associated (Fisher’s exact test) with good-prognosis features: patients’ age > 50 years (p = 4.28 × 10−9), lower pathological tumor grade (p = 2.12 × 10−21), smaller pathological tumor size (p = 4.42 × 10−4), positive ER status (p < 2.0 × 10−255), positive PR status (p < 2.0 × 10−255), negative HER2 status (p = 1.49 × 10−58), and HR+/HER2- subtype (p < 2.0 × 10−255).