ACE2 and infection: A 57-compound natural product library and a library of 462 ACE2 targeted inhibitors (the ACE2 receptor was identified to be necessary for SARS-CoV-2 infection [8]) were used in a pre-infection treatment screen to identify potential viral entry inhibitors, while a post-infection treatment screen was performed using both a 500 compound flavonoid library and a 1172 FDA-approved compound library in order to identify potential inhibitors targeting the post-entry steps of the SARS-CoV-2 replication cycle.