ACHE and early-onset autosomal dominant Alzheimer disease: Similarly, the phenolic and flavonoid contents of Elatostema papillosum showed significant antioxidant and inhibitory activity against AChE and butyrylcholinesterase (BChE) in Alzheimer’s disease, with IC50 values of 165.40 4.01 and 213.81 3.57 μg/mL, respectively [24].