ACHE and Cognitive impairment: Extract from the leaves of Ocimum basilicum (L.)containing 5,7-dihydroxy-3′,4′,5′-trimethoxyflavone and 3-hydroxy-3′,4′,5′-trimethoxyflavone mitigated cognitive impairment by reducing the concentrations of caspase-3, interleukine-6, interleukine-1β, TNF-α, and AChE activity in scopolamine-induced mice, and elevated levels of glutathione and IL-10 were also recorded in the hippocampal region of the brain [61].