CACNA1A and migraine disorder: Genetic studies investigating mechanistic insights underlying migraine subphenotypes revealed mutations in genes encoding the α1 subunit of the CaV2.1 P/Q-type voltage-gated Ca2+ channel (CACNA1A) and the α1 subunit of the neuronal NaV1.1 voltage-gated Na+ channel (SCN1A), respectively [15,16].