Both SCV2- and IAV-infected samples at 37 °C had uniquely higher expression of 18 genes in common, including APOBEC3 genes (APOBEC3A, APOBEC3B, and APOBEC3B-AS1), ssDNA binding protein SHOC1, and pseudogenes CLCA3P and NCF1B, suggesting higher chromatin instability during infection at higher temperatures (Supplementary Table S1). The gene discussed is SHOC1; the disease is infection.