Thus, the hyperkeratosis of KID syndrome may contribute to candidal colonization, based on a similar phenomenon seen in psoriasis [28]; however, the absence of superficial candidiasis in the latter (along with psoriasis being an IL-17-potentiated process [29,30]) suggests that hyperkeratosis per se is insufficient to increase the risk of fungal disease. The gene discussed is IL17A; the disease is psoriasis.