The prevalence of FD subtypes did not vary with the consumption of spicy foods or TRPV1 genotypes in a comparison of symptom generation according to these two factors, and TRPV1 polymorphisms were not associated with scores on symptom severity questionnaires, but eating spicy food was associated with higher scores for retching and stomach fullness [30]. The gene discussed is TRPV1; the disease is Fabry disease.