Furthermore, the increased SCFA production in the induction + DRBL and induction + DRBH groups was related to the decrease in pro-inflammatory markers, including TNF-α, IL-6, NF-κB, and COX-2, together with the reduction in the number of aberrant crypt foci (ACFs), and tumor formation in the colon in our previous study [26]. Here, NFKB1 is linked to neoplasm.