Likewise, the influence of CYP24A1 mRNA expression on survival in 3 types of cancer (lung, esophageal, and breast) was assessed in a multiethnic meta-analysis with 1479 cases in 4 studies; it revealed that elevated mRNA expression was associated with worse prognosis (HR = 1.24; 95% CI = 1.01–1.46; I2 = 38.1) [69]. Here, CYP24A1 is linked to cancer.