FGF21 and Hepatic fibrosis: In the NASHFit trial, aerobic exercise training was shown to improve liver fat, serum biomarkers of liver fibrosis, as well as cardiorespiratory fitness [12], and to further investigate this significant, unanswered question, we conducted a post hoc analysis of these data to determine the relationship between serum FGF21 and long-term aerobic exercise training in patients with NASH.