PNPLA3 and metabolic dysfunction-associated steatotic liver disease: Of the identified SNPs, three overlapped between the two GWAS using different definitions of NAFLD, and included well known NAFLD risk associated loci, such as the patatin-like phospholipase domain-containing protein 3 (PNPLA3)), transmembrane 6 superfamily 2 (TM6SF2), and glucokinase regulatory (GCKR) genes.