GPT and metabolic dysfunction-associated steatotic liver disease: While a systematic review and meta-analysis of sixteen randomized controlled trials in patients with NAFLD concluded that vitamin D supplementation could beneficially affect multiple anthropometric and biochemical indices (e.g., body weight and ALT) [47], a Cochrane review that more broadly focused on chronic liver disease in adults reported that vitamin D supplementation had no effect on liver function or steatosis in patients with NAFLD, but it cautioned that the evidence base for this (11 trials) was extremely weak [48].